de novo assembly

Variant detection and de novo assembly with HiFi reads

Applications update for comprehensive variant detection and de novo assembly with HiFi reads.

Advantages of HiFi reads for variant discovery and genome assembly

The PacBio Sequel II System is capable of generating highly accurate, long reads (HiFi reads) that can be used for variant detection and assembly. In this presentation, we demonstrate the utility and provide example workflows for variant detection, …

Single Molecule High-Fidelity (HiFi) Sequencing with >10 kb Libraries

Recent improvements in sequencing chemistry and instrument performance combine to create a new PacBio data type, Single Molecule High-Fidelity reads (HiFi reads). Increased read length and improvement in library construction enables average read …